O. Greengard, M. S. Yoss, J. A. del Valle
Jun 4, 1976
Citations
4
Influential Citations
75
Citations
Quality indicators
Journal
Science
Abstract
alpha-Methylphenylalanine reduces the phenylalanine hydroxylase activity of rat liver by 75 percent. Daily injections of this substance (plus phenylalanine) into rats from the 3rd to 15th day of age had no obvious toxic effects, and maintained a plasma concentration of phenylalanine comparable to that of phenylketonuric subjects.