N. Sugiyama, C. Kashima, Makoto Yamamoto*
Jul 1, 1966
Citations
0
Influential Citations
20
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
Alternaria Kikuchiana Tanaka is a fungus which produces a black spot disease in pears. The metabolite of this fungus contains a phytopathogenic substance for which the name “Altenin” has been proposed. A drop of an aqueous solution of altenin (2×10−5 mg./ml.) produces a black spot on pear leaves. The stability of altenin at 80, 60, and 40°C, and the behavior of altenin in relation to some adsorbents and solvents, were studied. Its isolation from the culture filtrate was found to be properly accomplished by adsorption with active charcoal, elution with acetone, and chromatography with silica gel and alumina columns. By these procedures, besides altenin, six metabolites, diheptyl phthalate, myristic acid, succinic acid, and the ester of C15-carboxylic acid, C19-steroid and trihydroxy anthraquinone, were obtained.