A. Ivanova, R. Kombarov, P. V. Davidenko
Jun 1, 2005
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Journal
Chemistry of Heterocyclic Compounds
Abstract
On the basis of 1H-1H two dimensional NMR spectroscopy (NOESY) it has been unambiguously shown that the benzylation of 2-[N-(4-chlorophenyl)carbamoyl]methylthio-4-phenyl-1H-imidazole occurs at the N(1) atom. This data was confirmed by comparison of the properties of the alkylation product obtained with the corresponding N(3)-benzylimidazole isomer synthesized independently.