Daniel Niederer, J. Kapron, J. Vederas
Oct 22, 1993
Citations
0
Influential Citations
22
Citations
Journal
Tetrahedron Letters
Abstract
Abstract N-Cbz-3-phenyloxaziridine can be generated in a two step process. This is a new reagent for direct electrophilic N-amination of chiral α-amino acids and their derivatives which affords the corresponding hydrazino acids protected with a readily removable N-Cbz group. Application of this methodology to a facile synthesis of l -hydrazino serine, a potentially useful biological tool, is described.