A. Terada, A. Hassner
Sep 1, 1969
Citations
0
Influential Citations
4
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
As part of search for a potential new type of antimalarial, several 1-(1′-phenyl-2′-aminoethyl)-5-methyltetrazoles were prepared by the amination of 1-(1′-phenyl-2′-bromoethyl)-5-methyltetrazole using various amines, such as mono- and diamines of aliphatic and alicyclic. The reaction in the presence of a large excess of amine occurred smoothly on heating at 100–130°C, and it gave the title product without any significant by-product such as the bistetrazole compound, even though a primary amine was used.