M.‐S. Wu, J. Liang, Y-D. Lin
Jun 1, 2008
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0
Influential Citations
29
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Quality indicators
Journal
British Journal of Pharmacology
Abstract
Aminoguanidine (AG), an inhibitor of advanced glycation endproducts, has been shown to prevent arterial stiffening and cardiac hypertrophy in streptozotocin (STZ) and nicotinamide (NA)‐induced type 2 diabetes in rats. Our aims were to examine whether AG produced benefits on cardiac pumping mechanics in the STZ and NA‐treated animals in terms of maximal systolic elastance (Emax) and theoretical maximum flow (Qmax).