Anastasiya N. Khrustaleva, K. Frolov, V. Dotsenko
Aug 1, 2017
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Influential Citations
3
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Journal
Chemistry of Heterocyclic Compounds
Abstract
The aminomethylation reaction of 9-benzyl-2,4-dioxo-3,9-diazaspiro[5.5]undecane-1,5-dicarbonitrile hydrochloride in the presence of primary aliphatic amines and an excess of 37% aqueous formaldehyde led to the formation of 7-substituted 1'-benzyl-2,4-dioxo-1H,5Hspiro[3,7-diazabicyclo[3.3.1]nonane-9,4'-piperidine]-1,5-dicarbonitrile derivatives.