G. Ege, H. Franz
May 1, 1984
Citations
0
Influential Citations
15
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
From the extent of the low field chemical shift of 4-H caused by exo-N-tosylation of 1-substituted 1H-pyrazolamines it is possible to distinguish between the 3- and 5-amino-isomers. The pyrazole substituent increment system of Tensmeyer and Ainsworth has been extended to 3- and 5-amino, 3- and 5-tosylamino, 1-benzyl and 1-tosyl substituents. By comparison of δ(4-H) values, calculated with the aid of these increments, with measured δ(4-H) values, a differentiation between 3- and 5-tosylaminopyrazoles but not between 3- and 5-aminopyrazoles can be made.