B. Duffau, Rossana Camila Laurie, Sonia Rojas
Sep 19, 2016
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Journal
JPC – Journal of Planar Chromatography – Modern TLC
Abstract
Synthetic drugs belong to the most common substances of abuse all over the world [1, 2]; in this scenario, important groups are constituted by hallucinogenic drugs [3], and in this context, numerous compounds have been described as new hallucinogenic drugs such as 25-B-NBOMe, 2-CB [4], and 1-(8-bromobenzo[1,2-b;4,5-b′]difuran-4-yl)-2-aminopropane, popularly known as Bromo-DragonFLY. The name of Bromo-DragonFLY results from the similarity of its molecular structure to a dragonfly due to the existence of two furan rings on opposing sides of a central phenyl ring forming the wings [5] (Figure 1). Bromo-DragonFLY, synthesized by Matthew A. Parker in 1998 during an investigation of serotonin receptor structure and activity [6], is a powerful, long-lasting, lysergic acid diethylamide (LSD)-like, hallucinogenic drug, which has been associated with a number of acute intoxications and fatalities in several countries [7]. It is usually compared with LSD due to its interaction with serotonin receptor, the similar effects, and ways of ingesting, but numerous reports affirm that it is even more dangerous than LSD, causing agitation, seizures, and aggressive hallucinations [8]; also, this drug could even be lethal at high doses [5]. Disturbingly, this drug can be found