M. Moneghini, F. Rubessa, P. Rupena
Aug 31, 1990
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Journal
International Journal of Pharmaceutics
Abstract
Abstract A rapid, specific and sensitive assay for the quantitation of chlorcyclizine hydrochloride and its degradation product by liquid chromatography is described. This method is used for stability studies. At 25°C, the predicted shelf-life in aqueous solution of 115 days makes liquid dosage forms of the drug inappropriate for storage conditions.