H. Dorn, A. Katritzky, M. Nesbit
1967
Citations
0
Influential Citations
1
Citations
Journal
Journal of The Chemical Society B: Physical Organic
Abstract
4-Hydroxy-1-methyl-4-phenylpiperidine is quaternised by ethyl bromoacetate to give 55 ± 2% of the isomer formed by equatorial approach. The orientations of the products formed were proved by the lactonisation (of the boat form) of that isomer which has an axial N-methyl group in the usual chair form.