C. Corral, R. Donoso, J. Elguero
Oct 1, 1990
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Influential Citations
1
Citations
Journal
Journal of Molecular Structure
Abstract
Abstract Conformation of 3-tert-butylamino-1-thienyloxy-2-propanol, a thiophene analogue of propanolol, have been theoretically investigated by molecular mechanics and semiempirical calculations. The conformational minima obtained have been compared with those reported for propranolol using molecular graphics. The good “fit” obtained can account for the similar biological activity of these compounds.