G. Krishnamoorthy, J. Ijaz Ahamed, S. Ramya
Jan 27, 2022
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Journal
YMER Digital
Abstract
It has been accomplished the development of a simple and rapid UVspectrophotometric method to estimate for the evaluation of Denaverine hydrochloride, which is used in the treatment of antispasmodic drug in Veterinary medicine. The present study describes the method developed a simple and reproducible. UV-Visible spectrophotometric method for the quantitative determination of Denaverine hydrochloride. A UV-Visible spectrophotometric method with 1cm quartz cells and distilled Methanol solvent was employed. The proposed method was successfully applied for the estimation of Denaverine hydrochloride in commercial pharmaceutical preparation with UV detection at 221 nm. It obey’s Beer law in the concentration range of 3 to 15μg/mL having correlation coefficient of 0.9997, Percentage recovery (100.0%). In terms of linearity, precision, accuracy, recovery, limit of detection (LOD), and limit of quantitation (LOQ), the developed technique was within limit as per ICH guidelines.