G. Caro, M. Massi, L. Micossi
Jul 1, 1982
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0
Influential Citations
19
Citations
Quality indicators
Journal
Peptides
Abstract
Abstract The angiotensin II analogues Sar 1 ,Ile 8 -,Sar 1 ,Leu 8 - and, to a lesser extent, Sar 1 ,Ala 8 - and Sar 1 -Gly 8 -angiotensin II proved to inhibit angiotensin-induced drinking in the pigeon, but did not significantly affect drinking induced by eledoisin or bombesin. The results suggest that the dipsogenic response elicited by bombesin or eledoisin, although almost identical to that evoked by angiotensin II, is mediated by the activation of central receptors different from those of angiotensin-induced drinking. These findings are consistent with the hypothesis that several peptidergic mechanisms are involved in the regulation of water intake.