T. Leniger, M. Wiemann, D. Bingmann
May 1, 2002
Citations
0
Influential Citations
68
Citations
Journal
Epilepsia
Abstract
Summary: Purpose: Sulthiame is a carbonic anhydrase (CA) inhibitor with an anticonvulsant effect in the treatment of benign and symptomatic focal epilepsy in children. The aim of the study was to elucidate the mode of action of sulthiame with respect to possible changes of intracellular pH (pHi) that might develop along with sulthiame's anticonvulsant properties.