Arun K. Ghosh, Jianfeng Li, R. S. Perali
Aug 2, 2006
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Influential Citations
20
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Journal
Synthesis
Abstract
A stereoselective synthesis of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol, an important high affinity P2-ligand, in high enantiomeric excess (>99%) is reported. The synthesis features an ester-derived titanium enolate based highly stereoselective anti-aldol reaction as the key step.