J. Bristol, R. Alekel, J. Fukunaga
Dec 1, 1978
Citations
0
Influential Citations
6
Citations
Quality indicators
Journal
Journal of medicinal chemistry
Abstract
The synthesis and antiallergic activity of a new series of 9H-xanthen-9-one-2-carboxylic acids are described. Antiallergic activity was evaluated in the rat passive cutaneous anaphylaxis (PCA) screen. Biological results were analyzed using regression analysis techniques, and the antiallergic activity of the compounds in the series was found to be highly correlated with substituent size.