L. Sukria, E K Hayati, A. Hanapi
Apr 8, 2020
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Quality indicators
Journal
IOP Conference Series: Earth and Environmental Science
Abstract
2-methoxy-4-((4-methoxyphenilimino)-methyl)-phenol compound is a Schiff base compound synthesized from vanillin and p-anisidin. The purpose of this research is to determine the stability of the 2-methoxy-4-((4-methoxyphenilimino) methyl) phenol compound and to test the anticancer activity of 2-methoxy-4-((4-methoxyphenilimino) methyl) phenol in inhibiting T47D breast cancer cells. The stability of the 2-methoxy-4-((4-methoxy-phenylimino)-methyl)- phenol compound was carried out by characterization using chemical tests, identification using FTIR and GC-MS. While the anticancer activity test of compound 2-methoxy-4-((4- methoxifenilimino) methyl) phenol using the MTT method. The results of re-characterization using chemical tests, identification of FTIR and KG-SM showed the compound was still stable. The IC50 value of compound 2-methoxy-4-((4-methoxyphenilimino) methyl) phenol was 353,038 μg/mL which showed weak activity in inhibiting T47D breast cancer cells.