C. Temple, G. Rener
Sep 1, 1989
Citations
0
Influential Citations
14
Citations
Journal
Journal of medicinal chemistry
Abstract
Racemic ethyl 5-amino-1,2-dihydro-2-methyl-3-phenylpyrido[3,4-b]pyrazine-7- carbamate (1a) has shown antitumor activity in a variety of in vivo experiments. The preparation of the R and S isomers gave compounds with significant differences in potency in several biological tests.