Dengfeng Dou, D. Alex, Bingfan Du
Oct 1, 2011
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0
Influential Citations
30
Citations
Journal
Bioorganic & medicinal chemistry
Abstract
A series of broad-spectrum antifungal agents based on the 1,2-benzisothiazol-3(2H)-one scaffold is reported. Preliminary structure-activity relationship studies have established the importance of the presence of the heterocyclic ring, a methyl group, and a phenyl ring for optimal manifestation of antifungal activity.