Bumorj Bulgantuy
2015
Citations
0
Influential Citations
2
Citations
Journal
Journal of Inner Mongolia University
Abstract
Safflower(petals of Carthamus tictorius)is an important traditional herbal drug.The present work focuses on the isolation,structure determination,and antioxidant activity of the chemical constituents of safflower.Hydroxysafflor yellow A,6-hydroxykaempferol-3,6,7-triglucoside,6-hydroxykaempferol-3-rutinoside-6-glucoside,6-hydroxykaempferol-3,6-diglucoside,kaempferol-3-Orutinoside,kaempferol-3-O-glucoside,isoquercitin,chlorogenic acid,syringin,protocatechuic acid,pcoumaric acid,and 8Z-decaene-4,6-diyne-1-O-β-D-glucopyranoside were isolated and identified.Their structures were determined by LC-MS and NMR analysis.The aglycone,6-hydroxykaempferol was obtained by hydrolysis of the major safflower flavonoid glycoside.Antioxidant test demonstrated that the flavonoid aglycones showed much stronger DPPH scavenging activity than the glycosides.The results suggest that 6-hydroxykaempferol and other flavonoid aglycones may play important roles for the in vivo bioactivity of safflower,as glycosides are known to metabolize to their aglycones in human.