K. Shindo, M. Kimura, Mayuko Iga
Jan 1, 2004
Citations
1
Influential Citations
38
Citations
Quality indicators
Journal
Bioscience, Biotechnology, and Biochemistry
Abstract
The potent antioxidative sesquiterpene, cacalol, was isolated from Cacalia delphiniifolia Sleb et Zucc, and identified by an analysis of the MS and NMR spectral data. Cacalol showed potent antioxidative activity in a rat brain homogenate model (IC50 of 40 nM). Cacalol also proved to be a potent neuroprotective substance which could protect neuronal hybridoma N18-RE-105 cells from L-glutamate toxicity.