Matthew M. Ippolito, J. Jacobson, M. Lederman
Oct 30, 2018
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Influential Citations
6
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Quality indicators
Journal
Clinical Infectious Diseases
Abstract
The effect of antiretroviral therapy (ART) on chloroquine and desethyl-chloroquine plasma concentrations was evaluated in clinical trial participants. Concentrations did not differ among participants receiving protease inhibitor-based ART (n = 9), efavirenz-based ART (n = 15), or other ART (n = 8) and those not receiving ART (n = 31). Efavirenz seemed to inhibit chloroquine desethylation.