Li Gui-ying
2012
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Quality indicators
Journal
Journal of Anhui Agricultural Sciences
Abstract
[Objective] To study the anti-tumor activity of CORTEX MELIAE extracts.[Method] The CORTEX MELIAE was extracted,and the inhibitive roles of the extracts on three tumor cells of human liver cancer BEL7402,lung cancer H460 and gastric cancer SGC-7901 were determined.[Result] Under high concentrations(50 and 100 μg/ml) of isotoosendamin and kulinone,the inhibitive rates on the three tumor cells all approximated or even exceeded 50%.But under high concentrations(50 and 100 μg/ml) of methylkulonate,kulactone,dubione B and kulonicacid,the three tumor cells were also obviously inhibited.The CORTEX MELIAE extracts contained certain cytotoxicity.[Conclusion] The CORTEX MELIAE extracts inhibited the growth of cell tumors.