Robert Brace Moffett, André Robert, Edward L. Schumann
1979
Citations
0
Influential Citations
7
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
A large number of pyridinecarboxaldehyde (and ketone) O-substituted oximes were prepared by alkylating the oxime or by treating the parent aldehyde (or ketone) with an O-substituted hydroxylamine. Many of these were converted to the N-oxide. Screening revealed that many of these oxime ethers were active in preventing gastric ulcers in rats. Data on selected examples is given.