H. Kaufman, C. Heidelberger
Aug 7, 1964
Citations
1
Influential Citations
157
Citations
Quality indicators
Journal
Science
Abstract
5-Trifluoromethyl-2'-deoxyuridine (F3TDR) has potent therapeutic antiviral activity in herpes simplex infection of the rabbit cornea with strains of herpes virus both sensitive and resistant to 5-iodo-2'-deoxyuridine, and in corneal infection with vaccinia. 5-Trifluoromethyl uracil is not therapeutically active in herpetic keratitis.