A. Lozynskyi, B. Zimenkovsky, Andriy Karkhut
Jul 27, 2016
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Influential Citations
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Journal
Tetrahedron Letters
Abstract
Abstract Novel thiopyrano[2,3- d ]thiazole derivatives were synthesized from 5-arylidene-4-thioxo-2-thiazolidinones and 2(5 H )furanone in 62–79% yields via hetero-Diels–Alder reactions and related acylation-based tandem processes. The reaction of 5-(4-fluorophenyl)-4-thioxo-2-thiazolidinone with 2(5 H )furanone was studied by DFT at the M06-2X/6-31+G(d,p) level. The stereo- and regioselectivities of cycloaddition were confirmed by NMR spectra and single-crystal X-ray diffraction analyses.