M. A. Radwan, M. Shaaban, E. Ragab
May 2, 2009
Citations
0
Influential Citations
13
Citations
Journal
Arkivoc
Abstract
3-Dimethylamino-2-(1H-indole-3-carbonyl)acrylonitrile (2) was treated with phenylhydrazine, in refluxing basic ethanol, afforded a single product N-1 or N-2 substituted pyrazole. Basic promoted cyclization of enaminonitrile 2 with α-heteroarylamines as N,N-1,3-dinucleophiles, condensed indolylpyrimidines as a new class of meridianine natural product analogs were obtained in moderate to good yields.