M. Ibrahim, A. Mohamad, A. M. Ahmed
2019
Citations
0
Influential Citations
2
Citations
Journal
Journal of Analytical & Pharmaceutical Research
Abstract
Tetramethrin](1,3-dioxo-4,5,6,7-tetrahydroisoindol-2-yl) methyl2,2-dimethyl-3-(2-methylprop-1-enyl) cyclopropane-1carboxylate [is a broad-spectrum, first-generation synthetic pyrethroid insecticide often used to target insects such as wasps, hornets, roaches, ants, fleas, and mosquitoes. It is oftentimes combined with another active ingredient for more broad range pest control, or for more effective long term treatments.1 Tetramethrin is commercially available in the form of lotion containing 0.006g of tetramethrin per mL combined with 0.024g of piperonyl butoxide per mL for topical treatment of pediculosis (lice infestations). Tetramethrin has a molecular formula of C19H25NO4 and molecular weight of 331.41g/mol.2 There are numerous different instrumental techniques used for the determination of tetramethrin. The available methods include voltammetric determination,3 capillary electrophoresis,4 spectrophotometric,5 as well as infrared spectrometric methods.6 However, the most widely applied techniques are chromatographic methods, such as gas chromatography (GC) with electron capture detection (ECD)7 or with mass spectrometry (MS),8 as well as high performance liquid chromatography (HPLC) with diode array (DAD)9 or with MS detection.10