Youwen Tang, Zhaofa Huang, Ting Yang
Jan 1, 2005
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0
Influential Citations
16
Citations
Journal
Analytical Letters
Abstract
Abstract Polymers imprinted with cefathiamidine were synthesized using 4‐vinylpyridine as an interacting monomer, ethyleneglycol dimethacrylate as a cross‐linker, and methanol and toluene as a porogen. The polymer was used as solid‐phase extraction sorbent. One‐hundred percent of the cefathiamidine was bound to the polymer and the target can be eluted efficiently only by 1 ml eluant. Human plasma and serum samples were preconcentrated by the molecularly imprinted solid‐phase extraction prior to analysis by HPLC. Recoveries of up to 98% were achieved. The molecularly imprinted solid phase extraction column can be used repeatedly. The Guangdong Natural Science Foundation (No. 31503) and Baiyunshan Chemical Pharmaceutical Factory in Guangzhou are gratefully acknowledged.