V. Tandon, Agarwal, A. Leusen
Feb 1, 1994
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0
Influential Citations
2
Citations
Journal
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry
Abstract
S-(+)-3-Hydroxytetrahydrofuran (1) on reaction with phenylglyoxallyl chloride (2) forms S-(+)-3-tetrahydrofuranyl benzoyformate (3) in 88% yield. Further reaction of the alpha-ketoester 3 with MeLi at - 95 degrees C followed by basic hydrolysis results in asymmetric synthesis of S-(+)-atrolactic acid (4) (e e 20%).