F. Bellina, R. Rossi*
Dec 1, 2002
Citations
0
Influential Citations
14
Citations
Journal
Synthesis
Abstract
3-Benzyl-4-isopropyl-2(5H)-furanone, which is a precursor to two naturally-occurring cytotoxic (Z)-5-ylidene-2(5H)-furanone derivatives, has been conveniently prepared from 3,4-di-bromo-2(5H)-furanone by a three-step proccdure involving two Pd-catalyzed cross-coupling reactions and a Rh(I)-catalyzed hydrogenation.