Mei-Hua Shen, Ying-Peng Pan, Zhi‐Hong Jia
Apr 22, 2015
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0
Influential Citations
20
Citations
Journal
Organic & biomolecular chemistry
Abstract
A method for convenient synthesis of N-alkyl-2-aryl-indole-3-carbaldehyde has been described. A variety of highly valuable indolyl aldehydes have been prepared through this method. Electron donating groups on both aromatic rings (anilinyl and benzyl) facilitate the formation of the desired products. A benzylic C-H insertion by rhodium carbene is the key step for this transformation.