O. Ghisalba, J. Nüesch
1981
Citations
0
Influential Citations
64
Citations
Journal
The Journal of antibiotics
Abstract
3-Amino-5-hydroxybenzoic acid was investigated for its ability to induce rifamycin biosynthesis in an appropriate mutant of Nocardia mediterranei and identified as a direct precursor of the seven-carbon amino starter-unit for the biosynthesis of ansamycins. A model for the biosynthesis of different types of ansamycins is presented and discussed.