Michael P. Doyle, Wenhao Hu, Iain M. Phillips
May 16, 2000
Citations
0
Influential Citations
45
Citations
Journal
Organic letters
Abstract
[reaction: see text] Effective synthetic uses of bisdiazocarbonyl compounds for the selective construction of diverse macrocycles, including the synthesis of patulolides A and B, by catalytic "carbene dimer" formation are reported. Control of stereochemistry and efficient methods for product isomerization or kinetic isomer differentiation have been achieved.