K. Scherer, K. Yamanouchi, Taizo Onox
Oct 1, 1990
Citations
0
Influential Citations
14
Citations
Journal
Journal of Fluorine Chemistry
Abstract
Abstract This paper describes a novel, safe, effective technique, with a new reactor design, for the synthesis of perfluorochemicals. This method, the liquid-phase photofluorination with undiluted fluorine, is applicable to the preparative-scale synthesis of isomerically-pure branched F-alkanes, F-ethers and F-tert-amines which are difficult to prepare by the classical fluorination methods ( i.e. electrochemical or CoF 3 ). The technique is based on the controlled inverse addition of the materials to be fluorinated to a well-stirred F 2 -saturated inert solvent, with simultaneous UV irradiation. The application of this method to the synthesis of F-ethers is described: the following were made by this method, F-2-propoxy-2-methyl-pentane, F-2-isobutoxy-2-methylpentane, F-n-heptylpropylether, F-2-pentoxy-2-methoxypropane, F-3-propoxy-2-methylpentane, F-2-ethyl-2-isopropyltetra-hydrofuran, F-3-isobutoxy-2-methylpentane, F-2-methoxy-4-ethyl-4-methyl-hexane, and F-2-methyl-(1-ethyl-1-methylpropyl)oxetane.