D. Tereshchenko, Yu. V. Skornyakov, E. Shuvalova
Oct 1, 2007
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Journal
Moscow University Chemistry Bulletin
Abstract
A new approach to the synthesis of 2,3-substituted γ-aminobutyric acids is proposed. This method consists of the selective catalytic reduction of substituted 3-cyanopropanoic acid esters, which are generated in high yield in the reaction of disubstituted cyclopropenes with sodium cyanide in the corresponding alcohol.