G. Cardillo, M. Orena, M. Penna
1991
Citations
0
Influential Citations
30
Citations
Journal
Tetrahedron
Abstract
Abstract The synthesis of enantiomerically pure 5-iodomethylimidazolidin-2-ones ( 3a–c ) and ( 4a–c ) is reported, by means of iodocyclisation of allylic tosylureas ( 2a–c ). Starting from pure ( 3a ) and ( 4a ), a synthesis of both (R)- and (S)-2,3-diaminopropanoic acid is described. Furthermore the cyclisation of the homoallylic tosylurea ( 2d ), occurring with total diastereoselection, is depicted.