Yuvaraj Dommaraju, Shruti Bora, D. Prajapati
Aug 25, 2015
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Influential Citations
13
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Journal
Organic & biomolecular chemistry
Abstract
A concise and efficient approach to the synthesis of structurally diverse 6,8a-dihydropyrido[2,3-d]pyrimidine derivatives has been accomplished by a three-component reaction involving sulfonyl acetonitrile, an aromatic aldehyde, and 6-aminouracil. The method involves the domino Knoevenagel condensation/Michael addition/cyclization cascade in the presence of triethylamine in refluxing ethanol.