Z. Tribak, Alae Chda, M. Skalli
Oct 10, 2018
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0
Influential Citations
2
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Journal
International Journal of Chemistry and Technology
Abstract
A new series of 5-Chloroisatin derivatives were synthesied and characterises with different characterization methods such as 1 H-NMR and1 3 C-NMR spectroscopy, and then tested for their myorelaxant activity. Computational investigations of the compounds 1a-3a , 2b and 4b on the muscle-relaxing effects performance were performed by using the DFT method with B3LYP functional . The result of descriptors calculation revealed that the theoretical approach was in good agreement with the reported experimental data.