I. Mieriņa, M. Jure, Agnese Stikute
Oct 5, 2016
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Influential Citations
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Journal
Chemistry of Heterocyclic Compounds
Abstract
This review summarizes strategies for the synthesis of 4-(het)aryl-3,4-dihydroquinolin-2(1H)-ones which are of interest due to their biological activity. It covers methods elaborated particularly for obtaining the title heterocycles, as well as procedures where these compounds are formed as side products. 4-Aryl-3,4-dihydroquinolin-2(1H)-one derivatives have been used for the synthesis of valuable molecules, e.g., anticancer drug tipifarnib.