D. Wallach, I. Csendes, Peter E. Burckhardt
Nov 7, 1984
Citations
0
Influential Citations
5
Citations
Journal
Helvetica Chimica Acta
Abstract
The synthesis of ethyl (2E, 4E, 8R)-8-methyl-10-[(2H-tetrahydropyran-2-yl)oxy]-2,4-decadienoate (11), methyl (2E, 8R)-8-methyl-10-[(2H-tetrahydropyran-2-yl)oxy]-2-decenoate (16), synthons for the construction of the macrocyclic moieties of the cytochalasins A, B and F, and of (3R)-[7-(1,3-dioxolan-2-yl)-3-methylheptyl]triphenyl-phosphonium bromide (24), a C8-building block for deoxaphomin, proxiphomin and protophomin is described. In all instances (+)-(R)-pulegone (5) served as starting material.