L. L. Winneroski, Y. Xu
Jul 23, 2004
Citations
0
Influential Citations
6
Citations
Journal
The Journal of organic chemistry
Abstract
Two complementary approaches to prepare 2-alkoxy carboxylic acids have been developed. Reductive ring opening of various 1,3-dioxolan-4-ones using TiCl(4)/Et(3)SiH or (t)BuMgCl affords the desired 2-alkoxy carboxylic acid in moderate to excellent chemical yield without loss of optical purity.