J. Rissing, T. Buxton, J. Fisher
Jul 1, 1985
Citations
2
Influential Citations
38
Citations
Quality indicators
Journal
Infection and Immunity
Abstract
Arachidonic acid was used as a facilitating agent in experimental rat Staphylococcus aureus osteomyelitis and compared with the more commonly used agent, sodium morrhuate. The injection of arachidonic acid or sodium morrhuate and S. aureus into rat tibiae caused increased quantitative bacterial bone counts, gross bone pathology, roentgenographic changes, and weight loss. The doses required to produce these changes appeared to be lower for arachidonic acid.