Haotian Ma, Cun-zhu Dong, Xue-ming Zhou
Jan 9, 2018
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0
Influential Citations
9
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Journal
Natural Product Research
Abstract
Abstract Three new aristololactam derivatives, aristololactam W–Y (1–3), and three known compounds (4–6) were isolated from the fruits of Aristolochia contorta Bunge. Compounds 1 and 2 represent the first example of an N-CH2OCH3 aristololactam derivative from natural products. Their structures were elucidated by 1D/2D NMR and HRESIMS spectra. All of the isolated compounds were evaluated for their insecticidal activity against 4th instar larvae of Aedes aegypti. Compound 4 displayed insecticidal activity with LC50 value of 3.54 μg/mL.