J. Beijnen, J. den Hartigh, W. Underberg
1985
Citations
0
Influential Citations
15
Citations
Journal
Journal of pharmaceutical and biomedical analysis
Abstract
The major degradation product in alkaline solution of mitomycin A, mitomycin C and porfiromycin is the corresponding 7-hydroxymitosane. The isolation and the physico-chemical and analytical properties of these compounds and their derivatized analogues are discussed. Data are presented on the degradation of mitomycin C at extremely high pH values.