S. Naveed, Zehra Ashraf, Tasleem Mukhtar
Nov 15, 2014
Citations
0
Influential Citations
6
Citations
Journal
Mintage Journal of Pharmaceutical and Medical Sciences
Abstract
Cefadroxil(7-[[amino-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-ene-2-carboxylic acid monohydrate)1 is a semisynthetic and new broad spectrum antibacterial showing both Gram +ve and gram –ve pathogens.The aim of study to calculate the percentage assay of different brands of cefadroxil by using rapid, economical and less time consuming spectrophotometric method.Five dilutions of 100ppm, 50ppm, 25ppm, 12.5ppm and 6.25ppm for each brand of cefadroxil were prepared and check absorbance and calculate %assay.The results are within the limit of USP/BP specifications. Thus we can conclude that the method can be applied for the routine QC quantitative analysis of cefadroxil in active and tablet formulation