Yanhan Yu, Ya-Nan Huang, Jun Deng
Feb 23, 2017
Citations
0
Influential Citations
21
Citations
Journal
Organic letters
Abstract
A facile synthetic approach to a series of chiral 4-chloromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one derivatives has been described. This transformation is achieved through the catalytic asymmetric chlorocyclization of 2-vinylphenylcarbamates using a newly developed organocatalyst. Furthermore, the resulting products can be easily converted into diverse bioactive agents.