Qing-Zhu Li, Jing Gu, Ying‐Chun Chen
Aug 21, 2014
Citations
0
Influential Citations
13
Citations
Journal
RSC Advances
Abstract
A highly regio- and stereoselective [4 + 2] formal cycloaddition process of cyclohexenylidenemalononitriles and α,β-unsaturated aldehydes has been developed by the catalysis of a chiral secondary amine, affording a range of bridged bicyclo[2.2.2]octane architectures with high molecular complexity (up to 98% ee, >19:1 d.r.).