Michail Tsakos, M. Elsegood, C. Kokotos
Feb 19, 2013
Citations
1
Influential Citations
48
Citations
Journal
Chemical communications
Abstract
The first organocatalytic asymmetric reaction between 1,4-cyclohexanedione and nitroalkenes has been studied, affording bicyclo[3.2.1]octane derivatives containing four continuous stereogenic centres. The products were obtained through a domino Michael-Henry process as a single diastereoisomer with excellent enantioselectivities.